Mitochondrial autophagy involving renal injury and aging is modulated by caloric intake in aged rat kidneys.

Mitochondrial autophagy involving renal injury and aging is modulated by caloric intake in aged rat kidneys.

BACKGROUND: A high-calorie (HC) diet induces renal injury and promotes aging, and calorie restriction (CR) may ameliorate these responses. However, the effects of long-term HC and CR on renal damage and aging have been not fully determined. Autophagy plays a crucial role in removing protein aggregat...

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Bibliographic Details
Main Authors: Jing Cui, Suozhu Shi, Xuefeng Sun, Guangyan Cai, Shaoyuan Cui, Quan Hong, Xiangmei Chen, Xue-Yuan Bai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3718786?pdf=render

Internet

http://europepmc.org/articles/PMC3718786?pdf=render

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