The Differential Distribution of RAPTA-T in Non-Invasive and Invasive Breast Cancer Cells Correlates with Its Anti-Invasive and Anti-Metastatic Effects

The Differential Distribution of RAPTA-T in Non-Invasive and Invasive Breast Cancer Cells Correlates with Its Anti-Invasive and Anti-Metastatic Effects

Nanoscale secondary ion mass spectrometry (NanoSIMS) combined with transmission electron microscopy (TEM) can be a powerful approach to visualize the exact distribution of drugs at the sub-cellular level. In this work, we exploit this approach to identify the distribution and localisation of the org...

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Bibliographic Details
Main Authors: Ronald F. S. Lee, Stéphane Escrig, Catherine Maclachlan, Graham W. Knott, Anders Meibom, Gianni Sava, Paul J. Dyson
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:International Journal of Molecular Sciences
Subjects:
breast cancer
invasion
metastasis
ruthenium
Online Access:https://www.mdpi.com/1422-0067/18/9/1869

Internet

https://www.mdpi.com/1422-0067/18/9/1869

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