Targeting MYCN in Pediatric and Adult Cancers

The deregulation of the MYC family of oncogenes, including c-MYC, MYCN and MYCL occurs in many types of cancers, and is frequently associated with a poor prognosis. The majority of functional studies have focused on c-MYC due to its broad expression profile in human cancers. The existence of highly...

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Bibliographic Details
Main Authors: Zhihui Liu, Samuel S. Chen, Saki Clarke, Veronica Veschi, Carol J. Thiele
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
MYC
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.623679/full