MUSASHI-Mediated Expression of JMJD3, a H3K27me3 Demethylase, Is Involved in Foamy Macrophage Generation during Mycobacterial Infection.

MUSASHI-Mediated Expression of JMJD3, a H3K27me3 Demethylase, Is Involved in Foamy Macrophage Generation during Mycobacterial Infection.

Foamy macrophages (FM)s harbor lipid bodies that not only assist mycobacterial persistence within the granulomas but also are sites for intracellular signaling and inflammatory mediators which are essential for mycobacterial pathogenesis. However, molecular mechanisms that regulate intracellular lip...

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Bibliographic Details
Main Authors: Sahana Holla, Praveen Prakhar, Vikas Singh, Anupama Karnam, Tanushree Mukherjee, Kasturi Mahadik, Pankti Parikh, Amit Singh, R S Rajmani, Subbaraya G Ramachandra, Kithiganahalli Narayanaswamy Balaji
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4988650?pdf=render

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http://europepmc.org/articles/PMC4988650?pdf=render

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