The Mevalonate Pathway, a Metabolic Target in Cancer Therapy

The Mevalonate Pathway, a Metabolic Target in Cancer Therapy

A hallmark of cancer cells includes a metabolic reprograming that provides energy, the essential building blocks, and signaling required to maintain survival, rapid growth, metastasis, and drug resistance of many cancers. The influence of tumor microenviroment on cancer cells also results an essenti...

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Bibliographic Details
Main Authors: Borja Guerra, Carlota Recio, Haidée Aranda-Tavío, Miguel Guerra-Rodríguez, José M. García-Castellano, Leandro Fernández-Pérez
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
mevalonate
cholesterol
oxysterols
isoprenoids
sterol regulatory element binding protein
cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.626971/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.626971/full

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