In vivo regulation of glycogen synthase kinase 3β activity in neurons and brains

Abstract Glycogen synthase kinase 3β (GSK3β) is a multifunctional protein kinase involved in many cellular activities including development, differentiation and diseases. GSK3β is thought to be constitutively activated by autophosphorylation at Tyr216 and inactivated by phosphorylation at Ser9. The...

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Bibliographic Details
Main Authors: Ambika Krishnankutty, Taeko Kimura, Taro Saito, Kyota Aoyagi, Akiko Asada, Shin-Ichiro Takahashi, Kanae Ando, Mica Ohara-Imaizumi, Koichi Ishiguro, Shin-ichi Hisanaga
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-09239-5