Short-Chain Fatty Acids Inhibit Growth Hormone and Prolactin Gene Transcription via cAMP/PKA/CREB Signaling Pathway in Dairy Cow Anterior Pituitary Cells

Short-Chain Fatty Acids Inhibit Growth Hormone and Prolactin Gene Transcription via cAMP/PKA/CREB Signaling Pathway in Dairy Cow Anterior Pituitary Cells

Short-chain fatty acids (SCFAs) play a key role in altering carbohydrate and lipid metabolism, influence endocrine pancreas activity, and as a precursor of ruminant milk fat. However, the effect and detailed mechanisms by which SCFAs mediate bovine growth hormone (GH) and prolactin (PRL) gene transc...

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Bibliographic Details
Main Authors: Jian-Fa Wang, Shou-Peng Fu, Su-Nan Li, Zhong-Ming Hu, Wen-Jing Xue, Zhi-Qiang Li, Bing-Xu Huang, Qing-Kang Lv, Ju-Xiong Liu, Wei Wang
Format: Article
Language:English
Published: MDPI AG 2013-10-01
Series:International Journal of Molecular Sciences
Subjects:
short-chain fatty acids
dairy cow
growth hormone
prolactin
G protein
Online Access:http://www.mdpi.com/1422-0067/14/11/21474

Internet

http://www.mdpi.com/1422-0067/14/11/21474

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