Sequence balance minimisation: minimising with unequal treatment allocations

Abstract Background Minimisation ensures excellent balance between groups for several prognostic factors, even in small samples. However, its use with unequal allocation ratios has been problematic. This paper describes a new minimisation scheme named sequence balance minimisation for unequal treatm...

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Bibliographic Details
Main Author: Vichithranie W. Madurasinghe
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Trials
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13063-017-1942-3