Sex-Dependent Motor Deficit and Increased Anxiety-Like States in Mice Lacking Autism-Associated Gene Slit3

Sex-Dependent Motor Deficit and Increased Anxiety-Like States in Mice Lacking Autism-Associated Gene Slit3

Altered neuronal connectivity has been implicated in the pathophysiology of Autism Spectrum Disorder (ASD). SLIT/ROBO signaling plays an important role in developmental processes of neuronal connectivity, including axon guidance, neuronal migration, and axonal and dendritic branching. Genetic eviden...

Full description

Bibliographic Details
Main Authors: Su Mi Park, Céline Plachez, Shiyong Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
autism(ASD)
Slit3
anxiety
hypolocomotion
motor coordination
Online Access:https://www.frontiersin.org/article/10.3389/fnbeh.2018.00261/full

Internet

https://www.frontiersin.org/article/10.3389/fnbeh.2018.00261/full

Similar Items