Methylation‐associated miR‐193b silencing activates master drivers of aggressive prostate cancer
Epigenetic silencing of miRNA is a primary mechanism of aberrant miRNA expression in cancer, and hypermethylation of miRNA promoters has been reported to contribute to prostate cancer initiation and progression. Recent data have shown that the miR‐193b promoter is hypermethylated in prostate cancer...
Main Authors: | Ying Z. Mazzu, Yuki Yoshikawa, Subhiksha Nandakumar, Goutam Chakraborty, Joshua Armenia, Lina E. Jehane, Gwo‐Shu Mary Lee, Philip W. Kantoff |
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Format: | Article |
Language: | English |
Published: |
Wiley
2019-09-01
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Series: | Molecular Oncology |
Subjects: | |
Online Access: | https://doi.org/10.1002/1878-0261.12536 |
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