Methylation‐associated miR‐193b silencing activates master drivers of aggressive prostate cancer

Epigenetic silencing of miRNA is a primary mechanism of aberrant miRNA expression in cancer, and hypermethylation of miRNA promoters has been reported to contribute to prostate cancer initiation and progression. Recent data have shown that the miR‐193b promoter is hypermethylated in prostate cancer...

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Bibliographic Details
Main Authors: Ying Z. Mazzu, Yuki Yoshikawa, Subhiksha Nandakumar, Goutam Chakraborty, Joshua Armenia, Lina E. Jehane, Gwo‐Shu Mary Lee, Philip W. Kantoff
Format: Article
Language:English
Published: Wiley 2019-09-01
Series:Molecular Oncology
Subjects:
Online Access:https://doi.org/10.1002/1878-0261.12536