Calculation of the free energy and cooperativity of protein folding.
Calculation of the free energy of protein folding and delineation of its pre-organization are of foremost importance for understanding, predicting and designing biological macromolecules. Here, we introduce an energy smoothing variant of parallel tempering replica exchange Monte Carlo (REMS) that al...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-05-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC1865387?pdf=render |