Chimeric antigen receptor (CAR)-modified natural killer cell-based immunotherapy and immunological synapse formation in cancer and HIV

ABSTRACT Cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells contribute to the body’s immune defenses. Current chimeric antigen receptor (CAR)-modified T cell immunotherapy shows strong promise for treating various cancers and infectious diseases. Although CAR-modified NK cell immunotherapy...

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Bibliographic Details
Main Authors: Dongfang Liu, Shuo Tian, Kai Zhang, Wei Xiong, Ndongala Michel Lubaki, Zhiying Chen, Weidong Han
Format: Article
Language:English
Published: SpringerOpen 2017-05-01
Series:Protein & Cell
Subjects:
HIV
Online Access:http://link.springer.com/article/10.1007/s13238-017-0415-5