Resveratrol Suppresses Oxidised Low-Density Lipoprotein-Induced Macrophage Apoptosis through Inhibition of Intracellular Reactive Oxygen Species Generation, LOX-1, and the p38 MAPK Pathway

Resveratrol Suppresses Oxidised Low-Density Lipoprotein-Induced Macrophage Apoptosis through Inhibition of Intracellular Reactive Oxygen Species Generation, LOX-1, and the p38 MAPK Pathway

Background/Aim: Resveratrol (RSV) may have therapeutic potential for various diseases. Here we investigated the effect of RSV on oxidised low-density lipoprotein- (ox-LDL) induced apoptosis in RAW264.7 macrophages. Methods: Apoptosis of macrophages following incubation with ox-LDL (with or without R...

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Bibliographic Details
Main Authors: Rong Guo, Yang Su, Baoxin Liu, Shuang Li, Shunping Zhou, Yawei Xu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
Resveratrol
Atherosclerosis
Macrophage apoptosis
ox-LDL
MAPK
Online Access:http://www.karger.com/Article/FullText/363026

Internet

http://www.karger.com/Article/FullText/363026

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