Current status and recent advances in reirradiation of glioblastoma

Abstract Despite aggressive management consisting of maximal safe surgical resection followed by external beam radiation therapy (60 Gy/30 fractions) with concomitant and adjuvant temozolomide, approximately 90% of WHO grade IV gliomas (glioblastomas, GBM) will recur locally within 2 years. For pati...

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Bibliographic Details
Main Authors: Giuseppe Minniti, Maximilian Niyazi, Filippo Alongi, Piera Navarria, Claus Belka
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Radiation Oncology
Subjects:
Online Access:https://doi.org/10.1186/s13014-021-01767-9