Effects of paclitaxel on EGFR endocytic trafficking revealed using quantum dot tracking in single cells.

Paclitaxel (PTX), a chemotherapeutic drug, affects microtubule dynamics and influences endocytic trafficking. However, the mechanism and the dynamics of altered endocytic trafficking by paclitaxel treatment in single living cells still remain elusive. By labeling quantum dots (QDs) to the epidermal...

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Bibliographic Details
Main Authors: Hui Li, Zhao-Wen Duan, Ping Xie, Yu-Ru Liu, Wei-Chi Wang, Shuo-Xing Dou, Peng-Ye Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3447934?pdf=render