A Strategy to Replace the Mouse Bioassay for Detecting and Identifying Lipophilic Marine Biotoxins by Combining the Neuro-2a Bioassay and LC-MS/MS Analysis

Marine biotoxins in fish and shellfish can cause several symptoms in consumers, such as diarrhea, amnesia, or even death by paralysis. Monitoring programs are in place for testing shellfish on a regular basis. In some countries testing is performed using the so-called mouse bioassay, an assay that f...

Full description

Bibliographic Details
Main Authors: Marcia Bodero, Arjen Gerssen, Liza Portier, Mirjam D. Klijnstra, Ron L. A. P. Hoogenboom, Leonardo Guzmán, Peter J. M. Hendriksen, Toine F. H. Bovee
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Marine Drugs
Subjects:
Online Access:https://www.mdpi.com/1660-3397/16/12/501