Targeting angiogenesis for fracture nonunion treatment in inflammatory disease

Abstract Atrophic fracture nonunion poses a significant clinical problem with limited therapeutic interventions. In this study, we developed a unique nonunion model with high clinical relevance using serum transfer-induced rheumatoid arthritis (RA). Arthritic mice displayed fracture nonunion with th...

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Bibliographic Details
Main Authors: Cuicui Wang, Jun Ying, Xiaolei Nie, Tianhong Zhou, Ding Xiao, Gaurav Swarnkar, Yousef Abu-Amer, Jianjun Guan, Jie Shen
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Bone Research
Online Access:https://doi.org/10.1038/s41413-021-00150-4