Protective effects of cannabidiol on lesion-induced intervertebral disc degeneration.

Disc degeneration is a multifactorial process that involves hypoxia, inflammation, neoinnervation, accelerated catabolism, and reduction in water and glycosaminoglycan content. Cannabidiol is the main non-psychotropic component of the Cannabis sativa with protective and anti-inflammatory properties....

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Bibliographic Details
Main Authors: João W Silveira, Ana Carolina Issy, Vitor A Castania, Carlos E G Salmon, Marcello H Nogueira-Barbosa, Francisco S Guimarães, Helton L A Defino, Elaine Del Bel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4269422?pdf=render