Stochasticity of replication forks' speeds plays a key role in the dynamics of DNA replication.
Eukaryotic DNA replication is elaborately orchestrated to duplicate the genome timely and faithfully. Replication initiates at multiple origins from which replication forks emanate and travel bi-directionally. The complex spatio-temporal regulation of DNA replication remains incompletely understood....
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-12-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1007519 |