The potential roles of Nrf2/Keap1 signaling in anticancer drug interactions
Nuclear factor (erythroid-derived 2)-related factor 2 (Nrf2), together with its suppressive binding partner Kelch-like ECH-associated protein 1 (Keap1), regulates cellular antioxidant response and drug metabolism. The roles of Nrf2/Keap1 signaling in the pathology of many diseases have been extensiv...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-01-01
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Series: | Current Research in Pharmacology and Drug Discovery |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2590257121000158 |