Role of pentraxin 3 in shaping arthritogenic alphaviral disease: from enhanced viral replication to immunomodulation.

Role of pentraxin 3 in shaping arthritogenic alphaviral disease: from enhanced viral replication to immunomodulation.

The rising prevalence of arthritogenic alphavirus infections, including chikungunya virus (CHIKV) and Ross River virus (RRV), and the lack of antiviral treatments highlight the potential threat of a global alphavirus pandemic. The immune responses underlying alphavirus virulence remain enigmatic. We...

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Bibliographic Details
Main Authors: Suan-Sin Foo, Weiqiang Chen, Adam Taylor, Kuo-Ching Sheng, Xing Yu, Terk-Shin Teng, Patrick C Reading, Helen Blanchard, Cecilia Garlanda, Alberto Mantovani, Lisa F P Ng, Lara J Herrero, Suresh Mahalingam
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-02-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1004649

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https://doi.org/10.1371/journal.ppat.1004649

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