AZT as a telomerase inhibitor

Telomerase is a highly specialized reverse transcriptase and the maintenance of telomeric length is determined by this specific enzyme. The human holoenzyme telomerase is a ribonucleoprotein composed by a catalytic subunit, hTERT, an RNA component, hTR, and a group of associated proteins. Telomerase...

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Bibliographic Details
Main Authors: Daniel E Gomez, Romina G Armando, Daniel F. eAlonso
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-09-01
Series:Frontiers in Oncology
Subjects:
AZT
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00113/full