Upregulation of TSHR, TTF-1, and PAX8 in Nodular Goiter Is Associated with Iodine Deficiency in the Follicular Lumen

Objective. It has been testified that iodine regulates thyroid function by controlling thyroid-restricted genes expression and is closely related to diffuse goiter and thyroid dysfunction. However, the effects of follicular lumen iodine, the main form of iodine reserve in the body, on thyroid-restri...

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Bibliographic Details
Main Authors: Huibin Huang, Lijun Chen, Bo Liang, Huiyao Cai, Qingyan Cai, Yaxiong Shi
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2016/2492450