Coilin association with Box C/D scaRNA suggests a direct role for the Cajal body marker protein in scaRNP biogenesis
Spliceosomal small nuclear ribonucleoproteins (snRNPs) are enriched in the Cajal body (CB). Guide RNAs, known as small Cajal body-specific RNAs (scaRNAs), direct modification of the small nuclear RNA (snRNA) component of the snRNP. The protein WRAP53 binds a sequence motif (the CAB box) found in man...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2014-07-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/3/4/240 |