Inactivation of Streptococcus mutans genes lytST and dltAD impairs its pathogenicity in vivo

Inactivation of Streptococcus mutans genes lytST and dltAD impairs its pathogenicity in vivo

Background: Streptococcus mutans orchestrates the development of a biofilm that causes dental caries in the presence of dietary sucrose, and, in the bloodstream, S. mutans can cause systemic infections. The development of a cariogenic biofilm is dependent on the formation of an extracellular matrix...

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Bibliographic Details
Main Authors: Midian C. Castillo Pedraza, Pedro L. Rosalen, Aline Rogéria Freire de Castilho, Irlan de Almeida Freires, Luana de Sales Leite, Roberta C. Faustoferri, Robert G. Quivey Jr, Marlise I. Klein
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Journal of Oral Microbiology
Subjects:
exopolysaccharides
edna
lipoteichoic acids
dental caries
systemic infection
oxidative stress
Online Access:http://dx.doi.org/10.1080/20002297.2019.1607505

Internet

http://dx.doi.org/10.1080/20002297.2019.1607505

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