Salivary dysbiosis in Sjögren’s syndrome and a commensal-mediated immunomodulatory effect of salivary gland epithelial cells
Abstract Salivary gland epithelial cells (SGECs) have been implicated in the pathogenesis of Sjögren’s syndrome due to aberrant antigen-presentation function. This study examined the hypothesis that oral dysbiosis modulates the antigen-presentation function of SGECs, which regulates CD4 T cell proli...
Main Authors: | Yu-chao Tseng, Hsin-yi Yang, Wei-ting Lin, Chia-bin Chang, Hsiu-chuan Chien, Hon-pin Wang, Chun-ming Chen, Jann-tay Wang, Chin Li, Shu-fen Wu, Song-chou Hsieh |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-03-01
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Series: | npj Biofilms and Microbiomes |
Online Access: | https://doi.org/10.1038/s41522-021-00192-w |
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