Salivary dysbiosis in Sjögren’s syndrome and a commensal-mediated immunomodulatory effect of salivary gland epithelial cells

Salivary dysbiosis in Sjögren’s syndrome and a commensal-mediated immunomodulatory effect of salivary gland epithelial cells

Abstract Salivary gland epithelial cells (SGECs) have been implicated in the pathogenesis of Sjögren’s syndrome due to aberrant antigen-presentation function. This study examined the hypothesis that oral dysbiosis modulates the antigen-presentation function of SGECs, which regulates CD4 T cell proli...

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Bibliographic Details
Main Authors: Yu-chao Tseng, Hsin-yi Yang, Wei-ting Lin, Chia-bin Chang, Hsiu-chuan Chien, Hon-pin Wang, Chun-ming Chen, Jann-tay Wang, Chin Li, Shu-fen Wu, Song-chou Hsieh
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:npj Biofilms and Microbiomes
Online Access:https://doi.org/10.1038/s41522-021-00192-w

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https://doi.org/10.1038/s41522-021-00192-w

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