Cell type-specific anti-cancer properties of valproic acid: independent effects on HDAC activity and Erk1/2 phosphorylation

<p>Abstract</p> <p>Background</p> <p>The anti-epileptic drug valproic acid (VPA) has attracted attention as an anti-cancer agent.</p> <p>Methods</p> <p>The present study investigated effects of VPA exposure on histone deacetylase (HDAC) inhibitio...

Full description

Bibliographic Details
Main Authors: Bock Elisabeth, Berezin Vladimir, Lepekhin Eugene A, Skladchikova Galina, Gotfryd Kamil, Walmod Peter S
Format: Article
Language:English
Published: BMC 2010-07-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/383