Virulence regulator EspR of Mycobacterium tuberculosis is a nucleoid-associated protein.

Virulence regulator EspR of Mycobacterium tuberculosis is a nucleoid-associated protein.

The principal virulence determinant of Mycobacterium tuberculosis (Mtb), the ESX-1 protein secretion system, is positively controlled at the transcriptional level by EspR. Depletion of EspR reportedly affects a small number of genes, both positively or negatively, including a key ESX-1 component, th...

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Bibliographic Details
Main Authors: Benjamin Blasco, Jeffrey M Chen, Ruben Hartkoorn, Claudia Sala, Swapna Uplekar, Jacques Rougemont, Florence Pojer, Stewart T Cole
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3315491?pdf=render

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http://europepmc.org/articles/PMC3315491?pdf=render

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