Comprehensive Integrative Analysis Reveals the Association of <i>KLF4</i> with Macrophage Infiltration and Polarization in Lung Cancer Microenvironment

Comprehensive Integrative Analysis Reveals the Association of <i>KLF4</i> with Macrophage Infiltration and Polarization in Lung Cancer Microenvironment

Macrophage polarization and infiltration to the tumor microenvironment (TME) is a critical determining factor for tumor progression. Macrophages are polarized into two states—M1 (pro-inflammatory, anti-tumorigenic and stimulated by LPS or <i>IFN-γ</i>) and M2 (anti-inflammatory pro-tumor...

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Bibliographic Details
Main Authors: Shweta Arora, Prithvi Singh, Shaniya Ahmad, Tanveer Ahmad, Ravins Dohare, Saleh A. Almatroodi, Faris Alrumaihi, Arshad Husain Rahmani, Mansoor Ali Syed
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cells
Subjects:
<i>KLF4</i>
tumor-associated macrophages (TAMs)
tumor microenvironment (TME)
non-small cell lung cancer (NSCLC)
macrophage polarization
<i>IL-1β</i>
Online Access:https://www.mdpi.com/2073-4409/10/8/2091

Internet

https://www.mdpi.com/2073-4409/10/8/2091

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