Eukaryotic translation initiation factors as promising targets in cancer therapy

Abstract The regulation of the translation of messenger RNA (mRNA) in eukaryotic cells is critical for gene expression, and occurs principally at the initiation phase which is mainly regulated by eukaryotic initiation factors (eIFs). eIFs are fundamental for the translation of mRNA and as such act a...

Full description

Bibliographic Details
Main Authors: Peiqi Hao, Jiaojiao Yu, Richard Ward, Yin Liu, Qiao Hao, Su An, Tianrui Xu
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Cell Communication and Signaling
Subjects:
eIF
Online Access:http://link.springer.com/article/10.1186/s12964-020-00607-9