Formulation optimization of scutellarin-loaded HP-β-CD/chitosan nanoparticles using response surface methodology with Box–Behnken design

The aim of this paper is to investigate and optimize the preparation of scutellarin (SCU)-loaded HP-β-CD/chitosan (CS) nanoparticles (CD/CS-SCU-NPs). CD/CS-SCU-NPs were prepared by ionic cross-linking method and the process and formulation variables were optimized using response surface methodology...

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Bibliographic Details
Main Authors: Shanshan Liu, Paul C. Ho
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087617300934