Dual-probe molecular MRI for the in vivo characterization of atherosclerosis in a mouse model: Simultaneous assessment of plaque inflammation and extracellular-matrix remodeling

Abstract Molecular MRI is a promising in-vivo modality to detect and quantify morphological and molecular vessel-wall changes in atherosclerosis. The combination of different molecular biomarkers may improve the risk stratification of patients. This study aimed to investigate the feasibility of simu...

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Bibliographic Details
Main Authors: Carolin Reimann, Julia Brangsch, Jan O. Kaufmann, Lisa C. Adams, David C. Onthank, Christa Thöne-Reineke, Simon P. Robinson, Bernd Hamm, Rene M. Botnar, Marcus R. Makowski
Format: Article
Language:English
Published: Nature Publishing Group 2019-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-50100-8