Power of multifactor dimensionality reduction and penalized logistic regression for detecting gene-gene Interaction in a case-control study
<p>Abstract</p> <p>Background</p> <p>There is a growing awareness that interaction between multiple genes play an important role in the risk of common, complex multi-factorial diseases. Many common diseases are affected by certain genotype combinations (associated with...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-12-01
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Series: | BMC Medical Genetics |
Online Access: | http://www.biomedcentral.com/1471-2350/10/127 |