Power of multifactor dimensionality reduction and penalized logistic regression for detecting gene-gene Interaction in a case-control study

<p>Abstract</p> <p>Background</p> <p>There is a growing awareness that interaction between multiple genes play an important role in the risk of common, complex multi-factorial diseases. Many common diseases are affected by certain genotype combinations (associated with...

Full description

Bibliographic Details
Main Authors: Brott Marcia J, Oetting William S, He Hua, Basu Saonli
Format: Article
Language:English
Published: BMC 2009-12-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/10/127