Genetic alteration of histone lysine methyltransferases and their significance in renal cell carcinoma

Background Histone lysine methyltransferases (HMTs), a category of enzymes, play essential roles in regulating transcription, cellular differentiation, and chromatin construction. The genomic landscape and clinical significance of HMTs in renal cell carcinoma (RCC) remain uncovered. Methods We condu...

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Bibliographic Details
Main Authors: Libin Yan, Yangjun Zhang, Beichen Ding, Hui Zhou, Weimin Yao, Hua Xu
Format: Article
Language:English
Published: PeerJ Inc. 2019-02-01
Series:PeerJ
Subjects:
RCC
Online Access:https://peerj.com/articles/6396.pdf