Sodium nitroprusside induces cell death and cytoskeleton degradation in adult rat cardiomyocytes in vitro: implications for anthracycline-induced cardiotoxicity

Sodium nitroprusside induces cell death and cytoskeleton degradation in adult rat cardiomyocytes in vitro: implications for anthracycline-induced cardiotoxicity

Sodium nitroprusside (SNP) is used clinically as a rapid-acting vasodilator and in experimental models as donor of nitric oxide (NO). High concentrations of NO have been reported to induce cardiotoxic effects including apoptosis by the formation of reactive oxygen species. We have therefore investig...

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Bibliographic Details
Main Authors: M. Chiusa, F. Timolati, J.C. Perriard, T.M. Suter, C. Zuppinger
Format: Article
Language:English
Published: PAGEPress Publications 2012-04-01
Series:European Journal of Histochemistry
Subjects:
cardiomyocytes, anthracyclines, nitric oxide, apoptosis, reactive oxygen species
Online Access:http://www.ejh.it/index.php/ejh/article/view/1890

Internet

http://www.ejh.it/index.php/ejh/article/view/1890

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