THE RELATIVE CONTRIBUTIONS OF GERMLINE VARIATION, EPIMUTATION, AND SOMATIC MUTATION TO PAEDIATRIC LEUKAEMIA PREDISPOSITION

THE RELATIVE CONTRIBUTIONS OF GERMLINE VARIATION, EPIMUTATION, AND SOMATIC MUTATION TO PAEDIATRIC LEUKAEMIA PREDISPOSITION

The next-generation sequencing era has repeatedly demonstrated that the amount of acquired somatic mutations in paediatric cancers can rarely account for the total incidence of any cancer subtype. In addition, many cancer-related mutations can be found in healthy individuals. These findings strongly...

Full description

Bibliographic Details
Main Author: Todd E. Druley
Format: Article
Language:English
Published: European Medical Journal 2016-07-01
Series:European Medical Journal Hematology
Subjects:
paediatric
cancer
predisposition
epimutation
genetics
Online Access:https://www.emjreviews.com/hematology/article/the-relative-contributions-of-germline-variation-epimutation-and-somatic-mutation-to-paediatric-leukaemia-predisposition/

Internet

https://www.emjreviews.com/hematology/article/the-relative-contributions-of-germline-variation-epimutation-and-somatic-mutation-to-paediatric-leukaemia-predisposition/

Similar Items