A SILAC-based screen for Methyl-CpG binding proteins identifies RBP-J as a DNA methylation and sequence-specific binding protein.

A SILAC-based screen for Methyl-CpG binding proteins identifies RBP-J as a DNA methylation and sequence-specific binding protein.

<h4>Background</h4>DNA methylation is an epigenetic modification that plays a crucial role in a variety of biological processes. Methylated DNA is specifically bound by Methyl-CpG Binding Proteins (MBPs). Three different types of MBPs have been identified so far: the Methyl-CpG Binding D...

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Bibliographic Details
Main Authors: Stefanie J J Bartels, Cornelia G Spruijt, Arie B Brinkman, Pascal W T C Jansen, Michiel Vermeulen, Hendrik G Stunnenberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21991380/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21991380/?tool=EBI

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