Cytomembrane nanovaccines show therapeutic effects by mimicking tumor cells and antigen presenting cells

Cancer vaccines often fail to generate clinically relevant effects. Here, the authors generate a nanosized cytomembrane vaccine based on fusion between dendritic cells and cancer cells, and show them to activate anti-tumor immune responses via their antigen presenting and T-cell activating functions...

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Bibliographic Details
Main Authors: Wen-Long Liu, Mei-Zhen Zou, Tao Liu, Jin-Yue Zeng, Xue Li, Wu-Yang Yu, Chu-Xin Li, Jing-Jie Ye, Wen Song, Jun Feng, Xian-Zheng Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2019-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11157-1