Characterization of pediatric cystic fibrosis airway epithelial cell cultures at the air-liquid interface obtained by non-invasive nasal cytology brush sampling

Characterization of pediatric cystic fibrosis airway epithelial cell cultures at the air-liquid interface obtained by non-invasive nasal cytology brush sampling

Abstract Background In vitro systems of primary cystic fibrosis (CF) airway epithelial cells are an important tool to study molecular and functional features of the native respiratory epithelium. However, undifferentiated CF airway cell cultures grown under submerged conditions do not appropriately...

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Bibliographic Details
Main Authors: Aline Schögler, Fabian Blank, Melanie Brügger, Seraina Beyeler, Stefan A. Tschanz, Nicolas Regamey, Carmen Casaulta, Thomas Geiser, Marco P. Alves
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Respiratory Research
Subjects:
Cystic fibrosis
Pediatric
Air-liquid interface
Airway epithelium
Cytology brush
Nasal brushing
Online Access:http://link.springer.com/article/10.1186/s12931-017-0706-7

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http://link.springer.com/article/10.1186/s12931-017-0706-7

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