Synthesis, Molecular Structure and Reactivity of 5-Methylidene-1,2,3,5-tetrahydroimidazo[2,1-b]quinazolines

Synthesis, Molecular Structure and Reactivity of 5-Methylidene-1,2,3,5-tetrahydroimidazo[2,1-b]quinazolines

Synthesis of novel 5-methylidene-1,2,3,5-tetrahydro[2,1-b]-quinazolinederivatives 2-4 with potential biological activities mediated by α-adrenergic and/orimidazoline receptors was performed by reacting 2-chloro-4,5-dihydroimidazole (1) withthe corresponding 2-aminoacetophenones. Compound 2, which...

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Bibliographic Details
Main Authors: Maria Gdaniec, Franciszek Sączewski, Anita Kornicka
Format: Article
Language:English
Published: MDPI AG 2004-02-01
Series:Molecules
Subjects:
5-Methylidene-1
2
3
5-tetrahydroimidazo[2
1-b]quinazolines
1
3-dipolar cycloaddition
alkylation
acylation
X-ray structure analysis.
Online Access:http://www.mdpi.com/1420-3049/9/3/86/

Internet

http://www.mdpi.com/1420-3049/9/3/86/

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