Co-administration of iloprost and eptifibatide in septic shock (CO-ILEPSS)—a randomised, controlled, double-blind investigator-initiated trial investigating safety and efficacy

Co-administration of iloprost and eptifibatide in septic shock (CO-ILEPSS)—a randomised, controlled, double-blind investigator-initiated trial investigating safety and efficacy

Abstract Background Part of the pathophysiology in septic shock is a progressive activation of the endothelium and platelets leading to widespread microvascular injury with capillary leakage, microthrombi and consumption coagulopathy. Modulating the inflammatory response of endothelium and thrombocy...

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Bibliographic Details
Main Authors: Rasmus Ehrenfried Berthelsen, Sisse Rye Ostrowski, Morten Heiberg Bestle, Per Ingemar Johansson
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Critical Care
Subjects:
Septic shock
Pathologic processes
Infection
Endothelium
Platelets
Iloprost
Online Access:http://link.springer.com/article/10.1186/s13054-019-2573-8

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http://link.springer.com/article/10.1186/s13054-019-2573-8

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