Hepatic 7α-hydroxylation of cholesterol in ascorbate-deficient and ascorbate-supplemented guinea pigs
Cholesterol 7α-hydroxylase activity was assayed in liver microsomes from guinea pigs supplemented with ascorbate and from guinea pigs in a state of ascorbate deficiency. A mass fragmentographic method was used by which the 7α-hydroxylation of endogenous cholesterol could be measured. The 7α-hydroxyl...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
1976-07-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520349191 |