1H-NMR metabolomic biomarkers of poor outcome after hemorrhagic shock are absent in hibernators.

Hemorrhagic shock (HS) following trauma is a leading cause of death among persons under the age of 40. During HS the body undergoes systemic warm ischemia followed by reperfusion during medical intervention. Ischemia/reperfusion (I/R) results in a disruption of cellular metabolic processes that ulti...

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Bibliographic Details
Main Authors: Lori K Bogren, Carl J Murphy, Erin L Johnston, Neeraj Sinha, Natalie J Serkova, Kelly L Drew
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4161479?pdf=render