Deregulation of Frizzled Receptors in Hepatocellular Carcinoma
G protein-coupled receptors (GPCRs) have a substantial role in tumorigenesis and are described as a “cancer driver”. Aberrant expression or activation of GPCRs leads to the deregulation of downstream signaling pathways, thereby promoting cancer progression. In hepatocellular carcinoma (HCC), the Wnt...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-01-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | http://www.mdpi.com/1422-0067/19/1/313 |