KLF4 prevents epithelial to mesenchymal transition in human corneal epithelial cells via endogenous TGF-β2 suppression

Introduction: Krüppel-like factor 4 (KLF4) is considered one of the Yamanaka factors, and recently, we and others have shown that KLF4 is one of the transcription factors essential for reprogramming non-human corneal epithelial cells (HCECs) into HCECs. Since epithelial to mesenchymal transition (EM...

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Bibliographic Details
Main Authors: Satoko Fujimoto, Ryuhei Hayashi, Susumu Hara, Yuzuru Sasamoto, Jodie Harrington, Motokazu Tsujikawa, Kohji Nishida
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Regenerative Therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320419300756