Effect of RNA Interference Targeting STAT3 Gene Combined with Ultrasonic Irradiation and SonoVue Microbubbles on Proliferation and Apoptosis in Keratinocytes of Psoriatic Lesions

Effect of RNA Interference Targeting STAT3 Gene Combined with Ultrasonic Irradiation and SonoVue Microbubbles on Proliferation and Apoptosis in Keratinocytes of Psoriatic Lesions

Background: Signal transducer and activator of transcription 3 (STAT3) was strongly expressed and activated in psoriatic keratinocytes (KCs) and correlated with the severity of psoriasis. The study aimed to investigate the effects of STAT3 small interfering RNA (siRNA) combined with ultrasonic irrad...

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Bibliographic Details
Main Authors: Li-Wei Ran, Hao Wang, Dong Lan, Hong-Xia Jia, Si-Si Yu
Format: Article
Language:English
Published: Wolters Kluwer 2018-01-01
Series:Chinese Medical Journal
Subjects:
Apoptosis; Cell Proliferation; Keratinocytes; Microbubbles; Psoriasis; RNA Interference; Small Interfering RNA; STAT3 Transcription Factor
Online Access:http://www.cmj.org/article.asp?issn=0366-6999;year=2018;volume=131;issue=17;spage=2097;epage=2104;aulast=Ran

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http://www.cmj.org/article.asp?issn=0366-6999;year=2018;volume=131;issue=17;spage=2097;epage=2104;aulast=Ran

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