Enhanced efficiency of cell death by lysosome-specific photodamage

Abstract Mobilization of specific mechanisms of regulated cell death is a promising alternative to treat challenging illness such as neurodegenerative disease and cancer. The use of light to activate these mechanisms may provide a route for target-specific therapies. Two asymmetric porphyrins with o...

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Bibliographic Details
Main Authors: Tayana Mazin Tsubone, Waleska Kerllen Martins, Christiane Pavani, Helena Couto Junqueira, Rosangela Itri, Maurício S. Baptista
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-06788-7