Encircling the regions of the pharmacogenomic landscape that determine drug response

Abstract Background The integration of large-scale drug sensitivity screens and genome-wide experiments is changing the field of pharmacogenomics, revealing molecular determinants of drug response without the need for previous knowledge about drug action. In particular, transcriptional signatures of...

Full description

Bibliographic Details
Main Authors: Adrià Fernández-Torras, Miquel Duran-Frigola, Patrick Aloy
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Genome Medicine
Online Access:http://link.springer.com/article/10.1186/s13073-019-0626-x